Abstract |
Scleromyxedema is a rare mucinous disease without thyroid dysfunction, associated with a monoclonal gammopathy. The deposits of mucin in the skin and other organs such as the cardiovasculary system, determine the prognosis of the disease. A 74-year old patient with initial scleromyxedema is described, in whom a pulse therapy with melphalan was initiated already in the early stages of the disease. Four cycles of melphalan in combination with prednisolon led to a complete and sofar stable remission of the disease.
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Authors | K Schubert, A Stein, M Meurer |
Journal | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
(Hautarzt)
Vol. 53
Issue 7
Pg. 478-82
(Jul 2002)
ISSN: 0017-8470 [Print] Germany |
Vernacular Title | Initiales Skleromyxödem Erfolgreiche Therapie mit Melphalan. |
PMID | 12219271
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Aged
- Biopsy
- Diagnosis, Differential
- Drug Therapy, Combination
- Facial Dermatoses
(diagnosis, drug therapy, pathology)
- Female
- Humans
- Lichenoid Eruptions
(diagnosis, drug therapy, pathology)
- Melphalan
(administration & dosage, adverse effects)
- Myxedema
(diagnosis, drug therapy, pathology)
- Prednisolone
(administration & dosage, adverse effects)
- Skin
(pathology)
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