Hypouricaemia as a marker of a generalized proximal tubular damage in alcoholic patients.

Abstract

AIMS AND METHODS:

Hypouricaemia is not frequently encountered in alcoholic patients. Described herein is the case of a 69-year-old alcoholic patient.

RESULTS:

The patient presented with severe hypouricaemia (serum uric acid 95.2 micro mol/l) due to renal urate wasting associated with a cluster of other metabolic abnormalities in the context of a reversible generalized dysfunction of the proximal tubules that mimicked Fanconi syndrome.

CONCLUSIONS:

The underlying mechanisms of this rare presentation are discussed.

• Authors: Evagelos Liberopoulos, George Miltiadous, Moses Elisaf
• Journal: Alcohol and alcoholism (Oxford, Oxfordshire) (Alcohol Alcohol) 2002 Sep-Oct Vol. 37 Issue 5 Pg. 472-4 ISSN: 0735-0414 [Print] England
• PMID: 12217941 (Publication Type: Case Reports, Journal Article)

Chemical References

• Uric Acid

Topics

• Aged
• Alcoholism (blood)
• Humans
• Kidney Diseases (blood)
• Kidney Tubules, Proximal (metabolism, pathology)
• Male
• Uric Acid (blood)