Relative efficacy of DEPA and neem oil for repellent activity against Phlebotomus papatasi, the vector of leishmaniasis.

Abstract

The insect repellent N, N-diethylphenyl acetamide (DEPA) was compared with neem oil, a commercial preparation, for protection against 3 day old un-fed female of the sandfly, Phlebotomus papatasi, (Diptera: Psychodidae) under laboratory conditions on mouse. The percentage protection against sandfly bite provided by neem oil was significantly higher than DEPA when applied at 1% and 2% concentrations (p = 0.000, t = 21.474; df = 6 and p = 0.001, t = 5.960; df = 6 respectively). However, neem oil did not show any significant difference with DEPA at 5% (p = 0.1682, t = 0.15667; df = 6). This clearly indicates that at higher concentration (5%) both neem oil and DEPA exhibited similar repellent action against P. papatasi.

• Authors: R Srinivasan, M Kalyanasundaram
• Journal: The Journal of communicable diseases (J Commun Dis) Vol. 33 Issue 3 Pg. 180-4 (Sep 2001) ISSN: 0019-5138 [Print] India
• PMID: 12206037 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Acetamides
• Acetanilides
• Glycerides
• Insect Repellents
• Terpenes
• neem oil
• N,N-diethylphenylacetamide

Topics

• Acetamides (pharmacology)
• Acetanilides
• Animals
• Female
• Glycerides (pharmacology)
• Insect Repellents (pharmacology)
• Insect Vectors (drug effects, physiology)
• Leishmaniasis (parasitology, prevention & control)
• Male
• Mice
• Phlebotomus (drug effects, physiology)
• Terpenes (pharmacology)