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Non-medical exposure to radioiodines and thyroid cancer.

Abstract
The Chernobyl accident, which occurred 32 years after the accidental exposure of Marshall islanders, resulted in the exposure of neighbouring populations to a mixture of iodine isotopes and in an increased incidence of thyroid cancer. The highest thyroid doses were received by the youngest age groups. This review describes the existing evidence, and examines factors that may have increased the risk. It also stresses problems with contemporary thyroid measurements, and the lack of information on the sensitivity of the thyroid to short-lived iodine isotopes and iodine-131. Practical considerations for nuclear physicians, epidemiologists and thyroidologists are discussed in the light of this major accident.
AuthorsElif Hindié, Laurence Leenhardt, Françoise Vitaux, Nicole Colas-Linhart, Pascale Grosclaude, Pierre Galle, André Aurengo, B Bok
JournalEuropean journal of nuclear medicine and molecular imaging (Eur J Nucl Med Mol Imaging) Vol. 29 Suppl 2 Pg. S497-512 (Aug 2002) ISSN: 1619-7070 [Print] Germany
PMID12192552 (Publication Type: Journal Article, Review)
Chemical References
  • Cesium Radioisotopes
  • Iodine Radioisotopes
  • Radioactive Pollutants
  • Technetium
  • Iodine
Topics
  • Accidents
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Animals
  • Cesium Radioisotopes (adverse effects)
  • Child
  • Child, Preschool
  • Disease Susceptibility
  • Dose-Response Relationship, Radiation
  • Europe (epidemiology)
  • Female
  • Follow-Up Studies
  • Food Contamination, Radioactive
  • Humans
  • Incidence
  • Infant
  • Iodine (deficiency)
  • Iodine Radioisotopes (adverse effects, pharmacokinetics)
  • Male
  • Micronesia (epidemiology)
  • Middle Aged
  • Neoplasms, Radiation-Induced (etiology)
  • Nuclear Reactors
  • Nuclear Warfare
  • Radiation Dosage
  • Radiation Injuries, Experimental (etiology)
  • Radioactive Pollutants (adverse effects)
  • Republic of Belarus (epidemiology)
  • Risk
  • Technetium (adverse effects)
  • Thyroid Gland (radiation effects)
  • Thyroid Neoplasms (epidemiology, etiology)
  • Ukraine (epidemiology)

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