Case series: Adderall augmentation of serotonin reuptake inhibitors in childhood-onset obsessive compulsive disorder.

Abstract

Current pharmacological treatment of obsessive compulsive disorder involves the use of selective serotonin reuptake inhibitors (SSRIs). However, a large proportion of patients does not respond fully to these medications despite receiving optimal doses and concomitant cognitive-behavioral therapy. Finding efficacious augmentation strategies has become an important goal of researchers and clinicians working with this population. In this case series, we describe four patients with childhood-onset obsessive compulsive disorder, and with partial or no response to SSRI treatment, who subsequently had a reduction of their symptoms with Adderall augmentation.

• Authors: Thomas Owley, Soyna Owley, Bennett Leventhal, Edwin H Cook Jr
• Journal: Journal of child and adolescent psychopharmacology (J Child Adolesc Psychopharmacol) Vol. 12 Issue 2 Pg. 165-71 ( 2002) ISSN: 1044-5463 [Print] United States
• PMID: 12188985 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adderall
• Amphetamines
• Serotonin Uptake Inhibitors

Topics

• Adult
• Age of Onset
• Amphetamines (therapeutic use)
• Child
• Drug Synergism
• Drug Therapy, Combination
• Female
• Humans
• Male
• Obsessive-Compulsive Disorder (drug therapy, psychology)
• Selective Serotonin Reuptake Inhibitors (therapeutic use)