Intranasal immunization against influenza.

Abstract

Nasalflu is a novel influenza subunit vaccine, which is administered by the intranasal route using a spray device. Nasalflu is based on the virosomal concept which is registered in the EU as Epaxal Berna, a vaccine against Hepatitis A, and Inflexal Berna V, a subunit influenza vaccine. The virosome is a carrier system which delivers antigens to cells and is able to induce both B- and T-cell immunity. When virosomal vaccines are given parenterally, an immune response is elicited fast and sufficiently.

• Authors: Reinhard Glück
• Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine (J Aerosol Med) Vol. 15 Issue 2 Pg. 221-8 ( 2002) ISSN: 0894-2684 [Print] United States
• PMID: 12184872 (Publication Type: Journal Article, Review)

Chemical References

• Adjuvants, Immunologic
• Bacterial Toxins
• Influenza Vaccines

Topics

• Adjuvants, Immunologic
• Administration, Intranasal
• Bacterial Toxins (immunology)
• Escherichia coli
• Humans
• Influenza Vaccines (administration & dosage, immunology)
• Influenza, Human (prevention & control)