[Disseminated intravascular coagulation and acute renal failure in an infant. Treated with streptokinase and peritoneal dialysis (author's transl)].

Abstract

An infant, aged seven months, developed toxic shock with acute renal failure as a sequel to the development of hypertonic dehydration. The anuric phase persisted despite treatment of the dehydration and diuretic infusions. The coagulation tests showed signs of disseminated intravascular coagulation and so the child was given fibrinolytic therapy for 36 hours following initial heparinization. Excretion of urine recommenced 8 hours after the initiation of fibrinolytic therapy. Peritoneal dialysis was carried out in parallel with the fibrinolytic treatment without haemorrhagic complications. It was possible to terminate dialysis on the fourth day already and renal function subsequently recovered completely.

• Authors: W Muntean, U Goriup
• Journal: Wiener klinische Wochenschrift (Wien Klin Wochenschr) Vol. 87 Issue 23 Pg. 792-6 (Dec 12 1975) ISSN: 0043-5325 [Print] Austria
• Vernacular Title: Disseminierte intravasale Gerinnung und akutes Nierenversagen bei einem Sāugling
• PMID: 1216846 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Diuretics
• Fibrinolytic Agents
• Streptokinase

Topics

• Acute Kidney Injury (etiology, therapy)
• Dehydration (complications, therapy)
• Disseminated Intravascular Coagulation (drug therapy, therapy)
• Diuretics (therapeutic use)
• Fibrinolytic Agents (therapeutic use)
• Humans
• Infant
• Infusions, Parenteral
• Male
• Peritoneal Dialysis
• Shock, Septic (etiology)
• Streptokinase (administration & dosage, therapeutic use)