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Laparoscopic herniorrhaphy with porcine small intestinal submucosa: a preliminary study.

AbstractINTRODUCTION:
Using mesh or a synthetic prosthesis during the laparoscopic repair of inguinal hernias has been demonstrated to be safe and effective. A new material, porcine small intestinal submucosa (SIS mesh), has been successfully used in canine and rodent animal models with excellent results. This mesh is degradable and resorbable with a marked decrease in the possibility of becoming infected. However, the amount of fibroblast ingrowth is equal to that with polypropylene mesh.
METHODS:
A comparison was made between this new SIS mesh to repair 15 inguinal hernias in 12 patients and polypropylene mesh used in 12 similar patients. A preperitoneal approach with balloon dissection was used in all patients.
RESULTS:
Demographics were similar in both groups. The results were excellent and compared equally. Complications (seroma, discomfort) were minimal in both groups and were similar.
CONCLUSIONS:
Porcine small intestinal submucosa, SIS mesh, can be used for laparoscopic repair of inguinal hernias. Long-term follow-up will be necessary to confirm these preliminary results.
AuthorsDavid S Edelman
JournalJSLS : Journal of the Society of Laparoendoscopic Surgeons (JSLS) 2002 Jul-Sep Vol. 6 Issue 3 Pg. 203-5 ISSN: 1086-8089 [Print] United States
PMID12166756 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Polypropylenes
Topics
  • Adult
  • Aged
  • Animals
  • Female
  • Hernia, Inguinal (surgery)
  • Humans
  • Intestinal Mucosa (transplantation)
  • Intestine, Small
  • Laparoscopy
  • Male
  • Middle Aged
  • Polypropylenes
  • Swine

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