Gabapentin treatment of glossopharyngeal neuralgia: a follow-up of four years of a single case.

Abstract

Glossopharyngeal neuralgia causes intermittent, lancinanting pain, involving the posterior tongue and pharynx, with radiation to deep ear structures. There are different pharmacological therapies which are tried to treat the neuralgia: carbamazepin, phenytoin, diazepam, amytriptyline, phenobarbital, ketamine, and baclofen; there are also surgical treatment proposed in order to cure the neuralgia such as vascular decompression or electrical stimulation of the motor cortex controlateral to the pain area. We report a single case of a patient with glossopharyngeal neuralgia treated with Gabapentin, the first described, who was followed up for four years, who respond completely to the therapy and did not complain from side effects, reducing even the reminiscence of pain during the second cluster of crisis.

• Authors: Rita Moretti, Paola Torre, R M Antonello, Antonio Bava, G Cazzato
• Journal: European journal of pain (London, England) (Eur J Pain) Vol. 6 Issue 5 Pg. 403-7 ( 2002) ISSN: 1090-3801 [Print] England
• PMID: 12160515 (Publication Type: Case Reports, Journal Article)

Chemical References

• Acetates
• Amines
• Analgesics
• Analgesics, Opioid
• Anticonvulsants
• Cyclohexanecarboxylic Acids
• Carbamazepine
• Tramadol
• gamma-Aminobutyric Acid
• Gabapentin

Topics

• Acetates (therapeutic use)
• Amines
• Analgesics (therapeutic use)
• Analgesics, Opioid (therapeutic use)
• Anticonvulsants (adverse effects)
• Carbamazepine (adverse effects)
• Cyclohexanecarboxylic Acids
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Drug Therapy, Combination
• Female
• Follow-Up Studies
• Gabapentin
• Glossopharyngeal Nerve (drug effects, pathology, physiopathology)
• Glossopharyngeal Nerve Diseases (drug therapy, etiology, physiopathology)
• Humans
• Middle Aged
• Tramadol (therapeutic use)
• Treatment Outcome
• gamma-Aminobutyric Acid