Hypoglycaemia and lactic acidosis in a MALT non Hodgkin's lymphoma.

Abstract

Hypoglycaemia associated with lactic acidosis is a rare complication of lymphomas; only four cases have been previously reported. Recent studies provide evidence of direct consumption of glucose by the tumour cells, leading to lactic acidosis. We report the case of a 64-year-old patient with a gastric diffuse large B cell non-Hodgkin's lymphoma transformed from an indolent mucosa associated lymphoid tissue (MALT) lymphoma, admitted to our department for acute renal failure due to a tumour lysis syndrome. After recovery from renal failure, she developed severe hypoglycaemia and lactic acidosis refractory to therapy. She died after the onset of shock and coma.

• Authors: Gabriele Di Comite, Lorenzo Dagna, Piero M Piatti, Lucilla D Monti, Francesca Tantardini, Luisa Praderio
• Journal: Leukemia & lymphoma (Leuk Lymphoma) Vol. 43 Issue 6 Pg. 1341-2 (Jun 2002) ISSN: 1042-8194 [Print] United States
• PMID: 12153006 (Publication Type: Case Reports, Journal Article)

Topics

• Acidosis, Lactic (etiology)
• Acute Kidney Injury (etiology)
• Fatal Outcome
• Female
• Humans
• Hypoglycemia (etiology)
• Lymphoma, B-Cell, Marginal Zone (complications, metabolism)
• Middle Aged
• Stomach Neoplasms (complications, metabolism)
• Tumor Lysis Syndrome (complications)