Abstract | BACKGROUND: Chronic hypergastrinaemia causes gastric enterochromaffin cell proliferation and carcinoid tumours. The only reliable means to diagnose enterochromaffin cell changes/ carcinoids is by biopsy. AIM: METHODS: Consecutive patients (n=145) had the above assays and endoscopy with gastric biopsies. RESULTS: CONCLUSIONS:
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Authors | S Bashir, F Gibril, J V Ojeaburu, B Asgharian, L K Entsuah, G Ferraro, P Crafa, C Bordi, R T Jensen |
Journal | Alimentary pharmacology & therapeutics
(Aliment Pharmacol Ther)
Vol. 16
Issue 7
Pg. 1367-82
(Jul 2002)
ISSN: 0269-2813 [Print] England |
PMID | 12144588
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers, Tumor
- CHGA protein, human
- Chromogranin A
- Chromogranins
- Imidazoles
- Neoplasm Proteins
- methylimidazoleacetic acid
- Serotonin
- Hydroxyindoleacetic Acid
- Histamine
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
(analysis, blood, urine)
- Biopsy
- Carcinoid Tumor
(diagnosis, pathology)
- Chromogranin A
- Chromogranins
(blood)
- Female
- Gastrinoma
(blood, metabolism, urine)
- Histamine
(blood)
- Humans
- Hydroxyindoleacetic Acid
(urine)
- Imidazoles
(urine)
- Male
- Middle Aged
- Multiple Endocrine Neoplasia Type 1
(blood, diagnosis, urine)
- Neoplasm Proteins
(blood)
- Pancreatic Neoplasms
(blood, metabolism, urine)
- Prospective Studies
- Sensitivity and Specificity
- Serotonin
(blood)
- Stomach Neoplasms
(diagnosis, pathology)
- Zollinger-Ellison Syndrome
(metabolism)
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