Autoimmune progesterone dermatitis manifested as erythema annulare centrifugum: Confirmation of progesterone sensitivity by in vitro interferon-gamma release.

Abstract	Autoimmune progesterone dermatitis was manifested as deep-type erythema annulare centrifugum. Sensitivity to progesterone was studied in vivo by means of intradermal and patch tests, which revealed immediate-type and delayed-type hypersensitivity, respectively. Sensitivity to progesterone was further confirmed in vitro by results of an interferon-gamma release test, which imply a possible role for T(H)1-type cytokines in autoimmune progesterone dermatitis.
Authors	Sima Halevy, Arnon D Cohen, Eitan Lunenfeld, Nili Grossman
Journal	Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 47 Issue 2 Pg. 311-3 (Aug 2002) ISSN: 0190-9622 [Print] United States
PMID	12140482 (Publication Type: Case Reports, Journal Article)
Chemical References	Progesterone Interferon-gamma
Topics	Adult Autoimmune Diseases (complications, physiopathology) Cells, Cultured Drug Eruptions (complications, immunology, physiopathology) Erythema (etiology) Female Humans Interferon-gamma (metabolism) Intradermal Tests Lymphocytes (immunology) Menstruation Progesterone (adverse effects)

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