Use of lufenuron as a treatment for fungal endometritis in four mares.

Abstract

Lufenuron, a benzoylphenyl urea derivative, was evaluated as a treatment for endometrial fungal infections in 4 mares. Intrauterine lavage was performed with lufenuron suspended in sterile saline (0.9% NaCl) solution. Cytologic evaluation and fungal culture of the endometrium, as well as subsequent reproductive performance, were used to monitor efficacy of this treatment. Fungal endometritis in mares is associated with infertility. Treatment is often ineffective and costly, and recurrence following treatment is not uncommon. Intrauterine infusions of lufenuron were effective in eliminating fungal endometritis in the 4 mares of this report.

• Authors: Milan B Hess, Nikola A Parker, Beverly J Purswell, John D Dascanio
• Journal: Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 221 Issue 2 Pg. 266-7, 240 (Jul 15 2002) ISSN: 0003-1488 [Print] United States
• PMID: 12118592 (Publication Type: Case Reports, Journal Article)

Chemical References

• Benzamides
• Insecticides
• fluphenacur

Topics

• Animals
• Aspergillosis (drug therapy, veterinary)
• Benzamides (therapeutic use)
• Candidiasis (drug therapy, veterinary)
• Endometritis (drug therapy, microbiology, veterinary)
• Female
• Fertility
• Horse Diseases (drug therapy, microbiology)
• Horses
• Insecticides (therapeutic use)
• Recurrence
• Treatment Outcome
• Uterus (cytology, pathology)