[Coronary Spasm after Administration of Propranolol during Dobutamine Stress Echocardiography].

Dobutamine stress echocardiography, a highly useful and safe challenge test for myocardial ischemia, is being used increasingly. We report the case of a 37-year-old man with rest angina, repolarization abnormalities in precordial leads and normal coronary arteries who was referred for dobutamine-atropine stress echocardiography, which was negative for ischemia. However, after testing, upon injection of propranolol, the patient suffered chest pain associated with ST elevation and severe regional systolic abnormalities. After intravenous nitroglycerin administration, chest pain and electrocardiographic abnormalities disappeared quickly, and systolic motion became normal. This complication was interpreted as a coronary spasm. We discuss the causes for the spasm and the role that might have been played by the drugs employed.
AuthorsLucía Alvarez, José Zamorano, Luis Mataix, Carlos Almeria, Raúl Moreno, José Luis Rodrigo
JournalRevista española de cardiología (Rev Esp Cardiol) Vol. 55 Issue 7 Pg. 778-81 (Jul 2002) ISSN: 0300-8932 [Print] Spain
Vernacular TitleEspasmo coronario tras infusión de propranolol durante un ecocardiograma de estrés con dobutamina.
PMID12113709 (Publication Type: Case Reports, Comparative Study, English Abstract, Journal Article)
Chemical References
  • Adrenergic beta-Antagonists
  • Dobutamine
  • Propranolol
  • Adrenergic beta-Antagonists (adverse effects)
  • Adult
  • Angina Pectoris (chemically induced)
  • Chest Pain (diagnosis)
  • Dobutamine
  • Echocardiography
  • Electrocardiography
  • Follow-Up Studies
  • Humans
  • Male
  • Myocardial Ischemia (diagnosis, ultrasonography)
  • Propranolol (adverse effects)
  • Time Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: