Abstract | OBJECTIVE: Experimental studies demonstrate that beta-adrenergic agonists markedly stimulate alveolar fluid clearance if concentrations of 10(-6) M are achieved in alveolar fluid. However, no studies have determined whether aerosolized beta-adrenergic agonists are delivered to the distal air spaces of the lung in therapeutic concentrations in patients with pulmonary edema. DESIGN AND SETTING: MEASUREMENTS AND RESULTS: CONCLUSIONS:
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Authors | Kamran Atabai, Lorraine B Ware, Mary E Snider, Patrick Koch, Brian Daniel, Thomas J Nuckton, Michael A Matthay |
Journal | Intensive care medicine
(Intensive Care Med)
Vol. 28
Issue 6
Pg. 705-11
(Jun 2002)
ISSN: 0342-4642 [Print] United States |
PMID | 12107675
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Adrenergic beta-Agonists
- Aerosols
- Albuterol
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Topics |
- APACHE
- Adrenergic beta-Agonists
(administration & dosage, analysis, therapeutic use)
- Aerosols
- Aged
- Albuterol
(administration & dosage, analysis, therapeutic use)
- Dose-Response Relationship, Drug
- Extravascular Lung Water
(chemistry)
- Female
- Hospital Mortality
- Humans
- Male
- Middle Aged
- Pulmonary Edema
(pathology)
- Respiration, Artificial
- Respiratory Distress Syndrome
(blood, classification, drug therapy)
- Retrospective Studies
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