A case of flare syndrome.

Abstract

The authors describe a case of severe CMV retinitis in a young adult AIDS patient who recovered following first a course of ganciclovir and then HAART. Six months after the initial episode while still under successful HAART, the patient developed an acute episode of retinitis despite a persistent significant improvement in the immunological picture and a very low level of CMV reactivation. The acute episode can be related to an enhanced individual reactivity to minor CMV replication.

• Authors: A Maiello, D Racca, D A Zeme, M Quario, A Sinicco, G Di Perri
• Journal: Le infezioni in medicina (Infez Med) Vol. 9 Issue 3 Pg. 176-7 (Sep 2001) ISSN: 1124-9390 [Print] Italy
• PMID: 12087220 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antiviral Agents
• Organophosphonates
• Organophosphorus Compounds
• Lamivudine
• Zidovudine
• Indinavir
• Cytosine
• Cidofovir
• Ganciclovir

Topics

• AIDS-Related Opportunistic Infections (etiology)
• Acute Disease
• Adult
• Antiretroviral Therapy, Highly Active
• Antiviral Agents (therapeutic use)
• CD4 Lymphocyte Count
• Cidofovir
• Cytomegalovirus Retinitis (etiology)
• Cytosine (analogs & derivatives, therapeutic use)
• Drug Therapy, Combination
• Ganciclovir (therapeutic use)
• HIV Infections (drug therapy)
• Humans
• Indinavir (administration & dosage)
• Lamivudine (administration & dosage)
• Male
• Organophosphonates
• Organophosphorus Compounds (therapeutic use)
• Zidovudine (administration & dosage)