Lyral 5% pet. was tested in 3245 consecutive patch test patients in 20 departments of dermatology in order (i) to check the diagnostic quality of this patch test preparation, (ii) to examine concomitant reactions to
Lyral and fragrance mix (FM), and (iii) to assess the frequency of contact
allergy to
Lyral in an unselected patch test population of German dermatological clinics. 62 patients reacted to
Lyral, i.e. 1.9%. One third of the positive reactions were + + and + + +. The reaction index was 0.27. Thus, the test preparation can be regarded a good diagnostic tool.
Lyral and fragrance mix (FM) were tested in parallel in 3185 patients. Of these, 300 (9.4%) reacted to FM, and 59 (1.9%) to
Lyral. In 40 patients, positive reactions to both occurred, which is 13.3% of those reacting to FM, and 67.8% of those reacting to
Lyral. So the concordance of positive test reactions to
Lyral and FM was only slight. Based on these results, the German
Contact Dermatitis Research Group (DKG) decided to add
Lyral 5% pet. to the standard series.