[Peliosis hepatis as the cause of liver affection in a patient treated with immunosuppressive agents].

Abstract

A case of peliosis hepatis in a 64-year-old woman treated with azathioprine because of a lung transplantation is described. The patient was admitted owing to epigastric pain and jaundice. Sixteen months before admission the patient had had a lung transplantation because of pulmonary emphysema. A liver biopsy showed multiple, dilated, blood-filled liver sinusoids consistent with peliosis hepatis. Besides azathioprine, the patient was treated with cyclosporine and prednisolone, but none of these drugs are known to be responsible for the development of peliosis hepatis. This rare condition, which causes liver affection in patients treated with azathioprine, should be kept in mind.

• Authors: Anette Hygum Knudsen
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 164 Issue 24 Pg. 3215-6 (Jun 10 2002) ISSN: 0041-5782 [Print] Denmark
• Vernacular Title: Peliosis hepatis som årsag til leverpåvirkning hos en patient i behandling med immunosuppressiva.
• PMID: 12082771 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Immunosuppressive Agents
• Azathioprine

Topics

• Azathioprine (adverse effects)
• Female
• Humans
• Immunosuppressive Agents (adverse effects)
• Liver (drug effects)
• Middle Aged
• Peliosis Hepatis (chemically induced)