Cortical-sparing laparoscopic adrenalectomy in a patient with multiple endocrine neoplasia type IIA.

Abstract	We describe the case of a patient affected by multiple endocrine neoplasia type IIA with a new diagnosis of an asymptomatic right pheochromocytoma. The patient underwent laparoscopic adrenalectomy with adrenal sparing. The removal of the tumor was successful with preservation of about one third of the adrenal gland. At the time of the last follow-up, the patient is well with partial hypoadrenalism without replacement therapy. The limitations to cortical-sparing adrenalectomy imposed by traditional open surgery (small tumor with peripheral location) can be reconsidered using the laparoscopic approach. Laparoscopic cortical-sparing adrenalectomy should become the gold standard for treatment of bilateral pheochromocytoma. The advantages of this technique are its efficacy and its reduced invasiveness with a low rate of complications either during the operation or in the postoperative period. Moreover, the preservation of a portion of the adrenal cortex may prevent the need for a life-long steroid replacement therapy.
Authors	F Porpiglia, P Destefanis, S Bovio, B Allasino, F Orlandi, D Fontana, A Angeli, M Terzolo
Journal	Hormone research (Horm Res) Vol. 57 Issue 5-6 Pg. 197-9 ( 2002) ISSN: 0301-0163 [Print] Switzerland
PMID	12053093 (Publication Type: Case Reports, Journal Article)
Copyright	Copyright 2002 S. Karger AG, Basel
Chemical References	Drosophila Proteins Proto-Oncogene Proteins Thyroid Hormones Thyrotropin Calcitonin Proto-Oncogene Proteins c-ret Receptor Protein-Tyrosine Kinases Ret protein, Drosophila
Topics	Adrenal Cortex Adrenal Gland Neoplasms (diagnosis, genetics, surgery) Adrenalectomy (methods) Adult Calcitonin (blood) Carcinoma, Medullary (diagnosis) Drosophila Proteins Female Germ-Line Mutation Humans Laparoscopy Lymphatic Metastasis Multiple Endocrine Neoplasia Type 2a (genetics) Pheochromocytoma (diagnosis, genetics, surgery) Proto-Oncogene Proteins (genetics) Proto-Oncogene Proteins c-ret Receptor Protein-Tyrosine Kinases (genetics) Thyroid Hormones (blood) Thyroid Neoplasms (diagnosis) Thyrotropin (blood) Treatment Outcome

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