J wave and ST segment elevation in the inferior leads: a latent type of variant Brugada syndrome?

Abstract

In a patient referred for the evaluation of non-sustained monomorphic ventricular tachycardia on Holter recordings, ventricular fibrillation was electrically induced during electrophysiologic study. Despite the absence of structural heart diseases, his ECG revealed J wave and ST segment elevation in the inferior leads, which showed circadian variation and were augmented by the sodium channel blocker, pilsicainide. This case might lead us to notice a new concept, a 'latent' type of variant Brugada syndrome, and these ECG findings and changes might serve as its diagnostic sign.

• Authors: Makoto Sahara, Kouichi Sagara, Takeshi Yamashita, Tsuyoshi Abe, Hajime Kirigaya, Misao Nakada, Hiroyuki Iinuma, Long-Tai Fu, Hiroshi Watanabe
• Journal: Japanese heart journal (Jpn Heart J) Vol. 43 Issue 1 Pg. 55-60 (Jan 2002) ISSN: 0021-4868 [Print] Japan
• PMID: 12041890 (Publication Type: Case Reports, Journal Article)

Chemical References

• Sodium Channel Blockers
• Lidocaine
• pilsicainide

Topics

• Adult
• Bundle-Branch Block (diagnosis)
• Diagnosis, Differential
• Electrocardiography
• Humans
• Lidocaine (analogs & derivatives, pharmacology)
• Male
• Sodium Channel Blockers (pharmacology)
• Syndrome
• Tachycardia, Ventricular (diagnosis)
• Ventricular Fibrillation (diagnosis)