[Monthly cycles of 1-week therapy with itraconazole for patients with Tinea pedis].

Abstract

Monthly cycles of 1-week therapy with oral itraconazole at 200 mg daily for tinea pedis was assessed to determine its acceptability to patients. Thirty-four patients (17 men and 17 women) with intractable tinea pedis, with informed consent, took 200 mg of itraconazole once daily for one week over a month period until mycological studies showed negative results for up to 4 months. The overall mycological effectiveness was about 80% after this therapy. Information was also gathered on the influence of this therapy on the patients quality of life by questionnaires. Nineteen (70%) among the 27 patients who answered the questionnaire preferred this 1-week administration of itraconazole over a month-long period compared with continuous daily therapy. Twenty-two (81%) preferred this therapy over topical treatment. We recommend to this therapy be added for the treatment of intractable tinea pedis.

• Authors: Hiromi Kobayashi, Nobuyuki Mizuno, Takeshi Nakanishi, Kazuyoshi Fukai, Masamitsu Ishii, Kensuke Morimoto
• Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology (Nihon Ishinkin Gakkai Zasshi) Vol. 43 Issue 2 Pg. 73-7 ( 2002) ISSN: 0916-4804 [Print] Japan
• PMID: 12040363 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antifungal Agents
• Itraconazole

Topics

• Administration, Oral
• Antifungal Agents (administration & dosage)
• Drug Administration Schedule
• Female
• Humans
• Itraconazole (administration & dosage)
• Male
• Middle Aged
• Pulse Therapy, Drug
• Quality of Life
• Surveys and Questionnaires
• Tinea Pedis (drug therapy)