Abstract | BACKGROUND: METHODS: Patients with AMI (n=39) and stable angina (n=40) were compared with matched controls. Lipids and lipoproteins were selectively removed from plasma by absorption to Liposorb gel. Lipid hydroperoxide concentration in the gel was measured by a sensitive triiodide spectrophotometric technique. RESULTS:
Lipid hydroperoxide levels in AMI and stable angina were elevated (3.47+/-0.21 micromol/l, P<.001 and 3.76+/-0.24 micromol/l, P<.001) compared to controls (2.18+/-0.13 micromol/l). Previously, a concentration >3 mol/l was considered pathological. Using this criterion, we detected pathological lipid hydroperoxide concentrations in 10.3% of controls, 57.5% of AMI and 61.5% of angina patients. CONCLUSION:
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Authors | Diana A Gorog, Nabeel Ahmed, Graham J Davies |
Journal | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
(Cardiovasc Pathol)
2002 May-Jun
Vol. 11
Issue 3
Pg. 153-7
ISSN: 1054-8807 [Print] United States |
PMID | 12031767
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Angina Pectoris
(blood)
- Female
- Humans
- Lipid Peroxides
(blood)
- Male
- Middle Aged
- Myocardial Infarction
(blood)
- Reproducibility of Results
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