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Ectopic ACTH syndrome associated with ovarian steroid-cell tumor.

Abstract
Several cases of ovarian neoplasms resulting in Cushing's syndrome due to ectopic secretion of ACTH or ectopic secretion of F have been reported. Tumors producing ACTH include adenocarcinoma, androblastoma, Sertoli cell carcinoma, carcinoid tumor and teratoma. Cortisol secretion has been reported in ovarian steroid cell tumor (unclassified steroid cell tumor). We present a case of a 19-year-old woman with Cushing's syndrome in course of an ovarian steroid cell tumor with ectopic ACTH production. To our knowledge, it is the first reported case of ACTH secreting ovarian steroid cell tumor causing Cushing's syndrome.
AuthorsK Sworczak, K Blaut, M Malecha, A Lewczuk
JournalJournal of endocrinological investigation (J Endocrinol Invest) Vol. 25 Issue 4 Pg. 369-72 (Apr 2002) ISSN: 0391-4097 [Print] Italy
PMID12030610 (Publication Type: Case Reports, Journal Article, Review)
Topics
  • ACTH Syndrome, Ectopic (etiology)
  • Adult
  • Cushing Syndrome (etiology)
  • Female
  • Humans
  • Ovarian Neoplasms (complications, diagnostic imaging, pathology, surgery)
  • Tomography, X-Ray Computed
  • Treatment Outcome

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