Abstract | OBJECTIVE: DESIGN: RESULTS: Ninety-one of 125 patients used noninvasive IPPV part time for 1.9 +/- 1.3 yr, and 51 went on to require it full time for 6.3 +/- 4.6 yr. Of the 31 noninvasive IPPV users who died without access to the protocol, 20 died from respiratory causes and seven died from cardiac causes. None of the 34 full-time noninvasive IPPV users with access to the protocol underwent tracheotomy or died from respiratory complications during a period of 5.4 +/- 4.0 yr, whereas three died from heart failure. Five patients with no breathing tolerance were extubated or decannulated to continuous noninvasive IPPV. CONCLUSIONS: Noninvasive respiratory aids can prolong survival and permit extubation or decannulation of patients with Duchenne muscular dystrophy with no breathing tolerance.
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Authors | Elia Gomez-Merino, John R Bach |
Journal | American journal of physical medicine & rehabilitation
(Am J Phys Med Rehabil)
Vol. 81
Issue 6
Pg. 411-5
(Jun 2002)
ISSN: 0894-9115 [Print] United States |
PMID | 12023596
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Cause of Death
- Cough
(etiology)
- Humans
- Intermittent Positive-Pressure Ventilation
- Muscular Dystrophies
(mortality, therapy)
- Retrospective Studies
- Survival Analysis
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