Clear cell myomelanocytic tumor of the thigh: report of a unique case.

Abstract

The clear cell myomelanocytic tumor (CCMMT) is a recently reported and very rare member of the perivascular epithelioid cell family of tumors (PEComa). All CCMMTs reported to date have occurred in or immediately adjacent to the falciform ligament/ligamentum teres. We report a case of CCMMT that occurred in the right thigh of a 43-year-old woman. Histologic examination showed the classic features of CCMMT, and immunohistochemical studies confirmed co-expression of smooth muscle actin, HMB-45, and microphthalmia transcription factor.

• Authors: Andrew L Folpe, Jesse K McKenney, Zhiming Li, Steven J Smith, Sharon W Weiss
• Journal: The American journal of surgical pathology (Am J Surg Pathol) Vol. 26 Issue 6 Pg. 809-12 (Jun 2002) ISSN: 0147-5185 [Print] United States
• PMID: 12023589 (Publication Type: Case Reports, Journal Article)

Chemical References

• Actins
• Antigens, Neoplasm
• Biomarkers, Tumor
• DNA-Binding Proteins
• MITF protein, human
• Melanoma-Specific Antigens
• Microphthalmia-Associated Transcription Factor
• Neoplasm Proteins
• Transcription Factors

Topics

• Actins (metabolism)
• Adult
• Angiomyolipoma (pathology)
• Antigens, Neoplasm
• Biomarkers, Tumor
• DNA-Binding Proteins (metabolism)
• Diagnosis, Differential
• Epithelioid Cells (metabolism, pathology)
• Female
• Foam Cells (pathology)
• Humans
• Immunohistochemistry
• Melanocytes (metabolism, pathology)
• Melanoma-Specific Antigens
• Microphthalmia-Associated Transcription Factor
• Muscle Neoplasms (metabolism, pathology, surgery)
• Neoplasm Proteins (metabolism)
• Sarcoma (metabolism, pathology, surgery)
• Transcription Factors