[Morphological features of the thymus in heliotrin hepatitis upon administration of immunostimulators].

Abstract

Structural changes of thymus in heliotrin hepatitis were characterized by distinct dynamics which on the whole suggested the progressing hypoplasia of its cortex. Immunostimulants parandin and thymalin suppressed the extent of thymocyte destruction and stimulated their mitotic activity. Although these parameters did not reach the control levels, the significant deceleration of hypoplastic processes in thymus, particularly in its cortex, were detected. Effect of immunostimulants was independent on the time of their administration in respect to heliotrin injection.

• Authors: G G Kasymova, K R Tukhtaev
• Journal: Morfologiia (Saint Petersburg, Russia) (Morfologiia) Vol. 120 Issue 6 Pg. 42-7 ( 2001) ISSN: 1026-3543 [Print] Russia (Federation)
• Vernacular Title: Morfologicheskie osobennosti timusa pri geliotrinnom gepatite v usloviiakh vvedeniia immunostimuliatorov.
• PMID: 12016764 (Publication Type: Journal Article)

Chemical References

• Adjuvants, Immunologic
• Benzaldehydes
• Benzodioxoles
• Thymus Hormones
• thymalin
• piperonal

Topics

• Adjuvants, Immunologic (pharmacology)
• Animals
• Benzaldehydes (toxicity)
• Benzodioxoles
• Chemical and Drug Induced Liver Injury (pathology)
• Rats
• Thymus Gland (drug effects, pathology)
• Thymus Hormones (pharmacology)