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[Efficacy of specific immunotherapy in children with seasonal allergic rhinitis and conjunctivitis, sensitized to grass pollen].

Abstract
The aim of this study was the evaluation of efficacy of the specific immunotherapy using Pollinex for 3 years before the period of pollen dust in children with seasonal allergic rhinitis and conjunctivitis induced by grass pollen. The study was carried out in a group of 40 children aged 5-18 years, from the Outpatient Department of Immunology at the National Research Institute of Mother and Child. The children demonstrated clinical symptoms of seasonal allergic rhinitis with conjunctivitis and had a medical history typical for this disease. Diagnostic procedures including skin prick tests and estimation of specific IgE to grass pollen by Pharmacia - CAP system, gave positive results. The efficacy of therapy was monitored by a clinical score with 4-0 points, recording symptoms relating to intensity of rhinoedema, rhinorrhea, sneezing, itching, oedema, conjunctival congestion, pain and lacrimation. In the study group, 39 children (97%) with seasonal rhinitis and conjunctivitis treated by specific immunotherapy (Pollinex) improved. This was confirmed by a statistically significant difference. The results indicate that the specific immunotherapy is an effective treatment of seasonal allergic rhinitis with conjunctivitis in children sensitized to grass pollen.
AuthorsE Bulawa, G Borysewicz, K Markiewicz, P Derentowicz
JournalMedycyna wieku rozwojowego (Med Wieku Rozwoj) 2001 Oct-Dec Vol. 5 Issue 4 Pg. 351-8 Poland
Vernacular TitleSkuteczność immunoterapii swoistej u dzieci chorych na alergiczny sezonowy niezyt nosa z zapaleniem spojówek, uczulonych na pyłki traw.
PMID12004142 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Allergens
  • Antigens, Plant
  • Plant Extracts
  • Parietaria judaica pollen
Topics
  • Adolescent
  • Allergens (therapeutic use)
  • Antigens, Plant (therapeutic use)
  • Child
  • Child, Preschool
  • Conjunctivitis, Allergic (drug therapy, epidemiology)
  • Desensitization, Immunologic
  • Female
  • Humans
  • Male
  • Plant Extracts (therapeutic use)
  • Poaceae (adverse effects)
  • Poland (epidemiology)
  • Pollen (adverse effects)
  • Rhinitis, Allergic, Seasonal (drug therapy, epidemiology)
  • Time Factors
  • Treatment Outcome

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