Abstract |
The aim of this study was the evaluation of efficacy of the specific immunotherapy using Pollinex for 3 years before the period of pollen dust in children with seasonal allergic rhinitis and conjunctivitis induced by grass pollen. The study was carried out in a group of 40 children aged 5-18 years, from the Outpatient Department of Immunology at the National Research Institute of Mother and Child. The children demonstrated clinical symptoms of seasonal allergic rhinitis with conjunctivitis and had a medical history typical for this disease. Diagnostic procedures including skin prick tests and estimation of specific IgE to grass pollen by Pharmacia - CAP system, gave positive results. The efficacy of therapy was monitored by a clinical score with 4-0 points, recording symptoms relating to intensity of rhinoedema, rhinorrhea, sneezing, itching, oedema, conjunctival congestion, pain and lacrimation. In the study group, 39 children (97%) with seasonal rhinitis and conjunctivitis treated by specific immunotherapy ( Pollinex) improved. This was confirmed by a statistically significant difference. The results indicate that the specific immunotherapy is an effective treatment of seasonal allergic rhinitis with conjunctivitis in children sensitized to grass pollen.
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Authors | E Bulawa, G Borysewicz, K Markiewicz, P Derentowicz |
Journal | Medycyna wieku rozwojowego
(Med Wieku Rozwoj)
2001 Oct-Dec
Vol. 5
Issue 4
Pg. 351-8 Poland |
Vernacular Title | Skuteczność immunoterapii swoistej u dzieci chorych na alergiczny sezonowy niezyt nosa z zapaleniem spojówek, uczulonych na pyłki traw. |
PMID | 12004142
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Allergens
- Antigens, Plant
- Plant Extracts
- Parietaria judaica pollen
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Topics |
- Adolescent
- Allergens
(therapeutic use)
- Antigens, Plant
(therapeutic use)
- Child
- Child, Preschool
- Conjunctivitis, Allergic
(drug therapy, epidemiology)
- Desensitization, Immunologic
- Female
- Humans
- Male
- Plant Extracts
(therapeutic use)
- Poaceae
(adverse effects)
- Poland
(epidemiology)
- Pollen
(adverse effects)
- Rhinitis, Allergic, Seasonal
(drug therapy, epidemiology)
- Time Factors
- Treatment Outcome
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