[Use of polidez for treating patients with endarteritis obliterans of the lower extremities].

Abstract

To treat patients with chronic arterial occlusion of the lower extremities, the authors used 3% solution of low molecular polyvinyl alcohol in 0.9% sodium chloride solution-polydese. The substance was injected intravenously and intraarterially in a dosage of 10 ml per k Kg of weight. There was noted a good tolerance of the drug, and also the absence of toxic, pyrogenic and allergic reactions. In polydese therapy a marked improvement of the peripheral blood circulation was observed. The conducted clinical observations, laboratory studies have proved polydese to be the drug of a positive rheological effect.

• Authors: K I Litmanovich, S P Shcherbinina, L G Mikhaĭlova
• Journal: Vestnik khirurgii imeni I. I. Grekova (Vestn Khir Im I I Grek) Vol. 115 Issue 10 Pg. 62-67 (Oct 1975) ISSN: 0042-4625 [Print] Russia (Federation)
• Vernacular Title: Primenenie polideza dlia lecheniia bol'nykh obliteriruiushchim éndarteritom nizhnykh konechnosteĭ
• PMID: 1198827 (Publication Type: Journal Article)

Chemical References

• Drug Combinations
• Plasma Substitutes
• Polyvinyls
• polidez
• Sodium Chloride
• Polyvinyl Chloride
• Polyvinyl Alcohol
• Cholesterol

Topics

• Adult
• Arteriosclerosis Obliterans (drug therapy)
• Blood Circulation (drug effects)
• Blood Viscosity (drug effects)
• Cholesterol (blood)
• Chronic Disease
• Drug Combinations
• Endarteritis (drug therapy)
• Female
• Hemodynamics (drug effects)
• Humans
• Leg (blood supply)
• Male
• Middle Aged
• Molecular Weight
• Plasma Substitutes (administration & dosage, adverse effects, therapeutic use)
• Polyvinyl Alcohol
• Polyvinyl Chloride (administration & dosage)
• Polyvinyls (administration & dosage)
• Sodium Chloride (administration & dosage)