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Occurrence and genetic association of selected virulence factors in clinical Escherichia coli isolates.

Abstract
Occurrence of cnf1+ E. coli pathogenic strains among extraintestinal E. coli isolates was evaluated to explain an impact of cytotoxic necrotizing factor type 1 (CNF1) in human infections. A total of 120 E. coli isolates were characterized for presence of virulence factors cnf1- and pap--specific sequences by PCR, and the production of alpha-hemolysin using blood agar-plate test. Different association patterns among the detected virulence factors were obtained by comparison of various groups of clinical E. coli isolates. These differences probably reflect a potential impact of CNF1 in the colonization of vaginal environment.
AuthorsE Bogyiová, L Siegfried, M Kmetová, Z Sándorcínová, A Liptáková, E Biros
JournalFolia microbiologica (Folia Microbiol (Praha)) Vol. 47 Issue 1 Pg. 73-7 ( 2002) ISSN: 0015-5632 [Print] United States
PMID11980274 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Bacterial Toxins
  • Cytotoxins
  • Escherichia coli Proteins
  • Hemolysin Proteins
  • Hlya protein, E coli
  • cytotoxic necrotizing factor type 1
Topics
  • Adult
  • Bacterial Toxins (genetics, metabolism)
  • Child
  • Child, Preschool
  • Cytotoxins (genetics, metabolism)
  • Escherichia coli (genetics, pathogenicity)
  • Escherichia coli Infections (microbiology)
  • Escherichia coli Proteins (genetics, metabolism)
  • Female
  • Fimbriae, Bacterial (genetics)
  • Hemolysin Proteins (genetics, metabolism)
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Virulence (genetics)

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