Abstract |
A rabid dog invaded a Thai pig farm and severely mauled 11 adult pigs. This offered an opportunity to study efficacy of a human type post-exposure vaccine regimen with and without rabies immunoglobulin. A commercial veterinary tissue culture rabies vaccine and equine rabies immune globulin were used. All pigs survived for 1 year following the exposure. All animals developed detectable rabies neutralizing antibodies on day 7 and levels over 0.5IU/ml on day 14. This small study suggests that post-exposure rabies treatment using a proven human regimen, applied to valuable farm animals, can be safe and effective.
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Authors | Channarong Mitmoonpitak, Sukunya Limusanno, Pakamatz Khawplod, Veera Tepsumethanon, Henry Wilde |
Journal | Vaccine
(Vaccine)
Vol. 20
Issue 16
Pg. 2019-21
(May 15 2002)
ISSN: 0264-410X [Print] Netherlands |
PMID | 11972969
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antibodies, Viral
- Rabies Vaccines
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Topics |
- Animals
- Antibodies, Viral
(blood)
- Dogs
- Rabies
(therapy, veterinary)
- Rabies Vaccines
(therapeutic use)
- Swine
- Swine Diseases
(therapy)
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