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Post-exposure rabies treatment in pigs.

Abstract
A rabid dog invaded a Thai pig farm and severely mauled 11 adult pigs. This offered an opportunity to study efficacy of a human type post-exposure vaccine regimen with and without rabies immunoglobulin. A commercial veterinary tissue culture rabies vaccine and equine rabies immune globulin were used. All pigs survived for 1 year following the exposure. All animals developed detectable rabies neutralizing antibodies on day 7 and levels over 0.5IU/ml on day 14. This small study suggests that post-exposure rabies treatment using a proven human regimen, applied to valuable farm animals, can be safe and effective.
AuthorsChannarong Mitmoonpitak, Sukunya Limusanno, Pakamatz Khawplod, Veera Tepsumethanon, Henry Wilde
JournalVaccine (Vaccine) Vol. 20 Issue 16 Pg. 2019-21 (May 15 2002) ISSN: 0264-410X [Print] Netherlands
PMID11972969 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Viral
  • Rabies Vaccines
Topics
  • Animals
  • Antibodies, Viral (blood)
  • Dogs
  • Rabies (therapy, veterinary)
  • Rabies Vaccines (therapeutic use)
  • Swine
  • Swine Diseases (therapy)

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