[Scleredema adultorum in secondary hyperparathyroidism].

Abstract

Scleredema adultorum, or Buschke's scleredema, belongs to the group of mucinoses. It is characterised by thickened and indurated skin. Histopathology shows thickened dermis with an infiltration of mucin between swollen collagen bundles. There are reports about many associations with scleredema adultorum, e.g., with diabetes mellitus and multiple myeloma. One case is known with associated primary hyperparathyroidism. For the first time we report a case of scleredema adultorum and secondary hyperparathyroidism, in a 46-year-old patient. Both forms of hyperparathyroidism have increased levels of parathormone. Therefore, these increased levels could have an influence on collagen metabolism.

• Authors: N Jacob, U Gleichmann, R Stadler
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 53 Issue 2 Pg. 121-5 (Feb 2002) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Scleroedema adultorum bei sekundärem Hyperparathyreoidismus.
• PMID: 11963192 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Mucins
• Collagen

Topics

• Biopsy
• Collagen (metabolism)
• Female
• Humans
• Hyperparathyroidism, Secondary (complications, diagnosis, pathology)
• Middle Aged
• Mucins (metabolism)
• Scleredema Adultorum (complications, diagnosis, pathology)
• Skin (pathology)