HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Emergence of cotrimoxazole- and quinolone-resistant Campylobacter infections in bone marrow transplant recipients.

Abstract
Clinical and microbiological data were collected prospectively from 704 patients who underwent bone marrow transplantation (BMT) during an 11-year period (1991-2001), and the first two cases of Campylobacter infection occurring in BMT recipients in the pre-engraftment period were identified. The two cases occurred on days 2 and 3 post-BMT, respectively. Both patients had Campylobacter jejuni enteritis, and one case was complicated by bacteraemia. In both cases the presenting symptoms were indistinguishable from hospital-acquired pre-engraftment diarrhoea, which is commonly caused by Clostridium difficile. Both of the Campylobacter jejuni isolates were resistant to cotrimoxazole and ciprofloxacin. Both patients responded to intravenous meropenem and subsequently had uneventful marrow engraftment.
AuthorsS K P Lau, P C Y Woo, K W Leung, K Y Yuen
JournalEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (Eur J Clin Microbiol Infect Dis) Vol. 21 Issue 2 Pg. 127-9 (Feb 2002) ISSN: 0934-9723 [Print] Germany
PMID11939393 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Quinolones
  • Trimethoprim, Sulfamethoxazole Drug Combination
Topics
  • Adolescent
  • Bone Marrow Transplantation (adverse effects)
  • Campylobacter Infections (diagnosis, drug therapy, epidemiology)
  • Campylobacter jejuni (drug effects, isolation & purification)
  • Cohort Studies
  • Drug Resistance, Multiple
  • Female
  • Hong Kong (epidemiology)
  • Humans
  • Incidence
  • Infant
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Prospective Studies
  • Quinolones (pharmacology)
  • Sensitivity and Specificity
  • Trimethoprim, Sulfamethoxazole Drug Combination (pharmacology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: