Abstract | PURPOSE: To synthesize the evidence from landmark clinical studies of lipid-lowering pharmacotherapy and nurse management of hyperlipidemia, discuss issues related to nonadherence, and proposes strategies for achieving long-term cholesterol control. DATA SOURCES: All publications of lipid-lowering clinical trials related to pharmacotherapy for dyslipidemias were accessed from a thorough Medline Search and reviewed by two nurse experts. CONCLUSIONS: Randomized controlled studies provide compelling evidence that reduction of blood cholesterol with pharmacotherapy reduces both first and subsequent coronary events. Nonetheless, inadequate provider and patient adherence to guidelines for lipid lowering remains prevalent. Studies show that nurses provide safe and effective care for patients with abnormal lipids. IMPLICATIONS: This article assists nurse practitioners in playing an active role in the implementation of the National Cholesterol Education Program Adult Treatment Panel III Report to be released in Spring 2001, where a strong emphasis will be placed on multidisciplinary approaches and adherence.
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Authors | D M Becker, J K Allen |
Journal | Journal of the American Academy of Nurse Practitioners
(J Am Acad Nurse Pract)
Vol. 13
Issue 5
Pg. 200-7
(May 2001)
ISSN: 1041-2972 [Print] United States |
PMID | 11930470
(Publication Type: Journal Article, Meta-Analysis)
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Chemical References |
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Topics |
- Clinical Trials as Topic
- Evidence-Based Medicine
- Guideline Adherence
- Humans
- Hyperlipidemias
(drug therapy, nursing)
- Hypolipidemic Agents
(therapeutic use)
- Nursing Care
(standards)
- Patient Compliance
- Practice Guidelines as Topic
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