Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity.

Abstract

The green tea extract AR25 is an 80% ethanolic dry extract standardized at 25% catechins expressed as epigallocatechin gallate (EGCG). In vitro, green tea extract AR25 exerts a direct inhibition of gastric and pancreatic lipases and a stimulation of thermogenesis. In an open study, the effects of extract AR25 were evaluated in moderately obese patients. After 3 months, body weight was decreased by 4.6% and waist circumference by 4.48%. These results suggest the green tea extract AR25 to be a natural product for the treatment of obesity, which exerts its activity by several ways: inhibition of lipases and stimulation of thermogenesis.

• Authors: P Chantre, D Lairon
• Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology (Phytomedicine) Vol. 9 Issue 1 Pg. 3-8 (Jan 2002) ISSN: 0944-7113 [Print] Germany
• PMID: 11924761 (Publication Type: Clinical Trial, Journal Article, Multicenter Study)

Chemical References

• Plant Extracts
• Tea
• green tea extract AR25

Topics

• Administration, Oral
• Adult
• Aged
• Body Mass Index
• Camellia sinensis
• Chromatography, High Pressure Liquid
• Female
• France
• Humans
• Male
• Middle Aged
• Obesity (drug therapy)
• Phytotherapy
• Plant Extracts (administration & dosage, therapeutic use)
• Tea