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Poisoning as a result of barium styphnate explosion.

AbstractBACKGROUND:
Acute barium poisoning is most often the result of accidental or suicidal ingestion of the rodenticide, barium carbonate. We describe a trauma patient whose condition was complicated by severe acute barium toxicity from an explosion of the propellant, barium styphnate. In addition to critical injuries, the patient manifested classic signs of barium toxicity including repeated profound hypokalemia, cardiac arrhythmias, respiratory failure, prolonged gastrointestinal dysfunction, paralysis, myoclonus, hypertension, and profound lactic acidosis.
METHODS:
The patient required lidocaine for ventricular bigeminy, massive infusions of potassium, prolonged ventilatory support, and parenteral nutrition to manage the effects of barium toxicity.
RESULTS:
He is the first reported case to demonstrate recurrent profound hypokalemia as an effect of blood transfusions.
CONCLUSIONS:
Considering the paucity of information concerning management of this life-threatening problem, the pathophysiology of barium toxicity, including the transfusion related hypokalemia, and its management is reviewed.
AuthorsIra A Jacobs, Joseph Taddeo, Kathleen Kelly, Carl Valenziano
JournalAmerican journal of industrial medicine (Am J Ind Med) Vol. 41 Issue 4 Pg. 285-8 (Apr 2002) ISSN: 0271-3586 [Print] United States
PMID11920972 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright 2002 Wiley-Liss, Inc.
Chemical References
  • Barium Compounds
  • barium styphnate
  • Barium
Topics
  • Accidents, Occupational
  • Arrhythmias, Cardiac (chemically induced)
  • Barium (poisoning)
  • Barium Compounds (administration & dosage)
  • Explosions
  • Humans
  • Hypokalemia (chemically induced)
  • Male
  • Middle Aged
  • Poisoning (therapy)
  • Transfusion Reaction

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