The effect of artificial tears on corneal surface regularity in patients with Sjögren syndrome.

Abstract

PURPOSE:

To evaluate the effect of artificial tears on the topographic parameters associated with corneal surface regularity in patients with Sjögren syndrome.

METHODS:

A total of 38 eyes of 20 patients with Sjögren syndrome were evaluated prospectively. The mean age of the patients was 50.5 +/- 15.3 years (range, 28-76). Corneal topography with the Topographic Modeling System (TMS-2, Tomey) was performed before and after the instillation of artificial tears. The surface regularity index (SRI), surface asymmetry index (SAI), potential visual acuity (PVA) and mean astigmatism were compared in dry eyes before and after the instillation of artificial tears.

RESULTS:

Before the instillation of artificial tears SAI, SRI, PVA and mean antigmatism values were found to be 1.37 +/- 1.47, 0.74 +/- 0.42, 20/30.92 +/- 20/8.12 and 1.53 +/- 1.47 D, respectively. In corneal topography performed after the instillation of artificial tears SAI, SRI, PVA and mean astigmatism values were 0.71 +/- 0.82, 0.43 +/- 0.36, 20/25.92 +/- 20/5.55 and 1.08 +/- 1.18, respectively. When compared statistically, the SRI, SAI, and mean astigmatism all decreased significantly and the PVA improved (p = 0.0001).

CONCLUSION:

Irregular corneal surface in dry eye patients affects optical quality. The statistically significant improvement observed in SRI and SAI values after the instillation of artificial tears also improves the PVA that is especially related to SRI.

• Authors: Güzin Iskeleli, Melda Kizilkaya, Osman S Arslan, Sehirbay Ozkan
• Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde (Ophthalmologica) 2002 Mar-Apr Vol. 216 Issue 2 Pg. 118-22 ISSN: 0030-3755 [Print] Switzerland
• PMID: 11919437 (Publication Type: Journal Article)
• Copyright: Copyright 2002 S. Karger AG, Basel

Chemical References

• Ophthalmic Solutions

Topics

• Adult
• Aged
• Astigmatism (physiopathology)
• Cornea (drug effects, physiopathology)
• Corneal Topography
• Humans
• Middle Aged
• Ophthalmic Solutions (administration & dosage)
• Prospective Studies
• Sjogren's Syndrome (physiopathology)
• Visual Acuity (physiology)