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[Rectal administration of misoprostol for delivery induced hemorrhage. Preliminary study].

AbstractOBJECTIVE:
Assess the efficacy of one misoprostol tablet (Cytotec) in severe delivery-induced hemorrhage on uterine atony after failure of syntocinon.
PATIENTS AND METHODS:
A descriptive study was conducted at the Djibouti Army Hospital from September to December 2000. Five patients with severe delivery-induced hemorrhage due to uterine atony unresponsive to syntocinon were give a tablet of misoprostol by rectal administration.
RESULTS:
The hemorrhage ceased in less than 5 minutes in all patients. No immediate side effect was observed.
DISCUSSION:
These preliminary findings are encouraging and suggest that further investigations would be useful to assess the beneficial effect of misoprostol by rectal administration for patients with severe delivery-induced hemorrhage due to uterine atony. Case-control studies with a sufficient number of cases should be undertaken to determine the real efficacy of misoprostol in this indication.
AuthorsR Shojai, L Piéchon, C d'Ercole, L Boubli, J E Pontiès
JournalJournal de gynecologie, obstetrique et biologie de la reproduction (J Gynecol Obstet Biol Reprod (Paris)) Vol. 30 Issue 6 Pg. 572-5 (Oct 2001) ISSN: 0368-2315 [Print] France
Vernacular TitleLe misoprostol par voie rectale dans les hémorragies de la délivrance. Une étude préliminaire.
PMID11883024 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Oxytocics
  • Misoprostol
Topics
  • Administration, Rectal
  • Adolescent
  • Adult
  • Female
  • Humans
  • Misoprostol (administration & dosage, therapeutic use)
  • Oxytocics (administration & dosage, therapeutic use)
  • Postpartum Hemorrhage (drug therapy)
  • Pregnancy
  • Prospective Studies
  • Treatment Outcome

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