Evaluation of efficacy and safety of nimesulide with betacyclodextrin vs nimesulide tablets in osteoarthritis.

Abstract

Efficacy and safety of nimesulide as well as favourable tolerability have been tested in osteoarthritis in short term study and post-marketing survey. Here is a report which shows the superiority of nimesulide complexed with betacyclodextrin vs ninesulide tablet in osteoarthritis in a long term study.

• Authors: M Raja, A Sivaseelam, R Subbiah, N R Yuvaraj, K Chandran, K Annamalai
• Journal: Journal of the Indian Medical Association (J Indian Med Assoc) Vol. 99 Issue 8 Pg. 451-2 (Aug 2001) ISSN: 0019-5847 [Print] India
• PMID: 11881862 (Publication Type: Clinical Trial, Comparative Study, Journal Article)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Cyclodextrins
• Sulfonamides
• beta-Cyclodextrins
• betadex
• nimesulide

Topics

• Administration, Oral
• Adult
• Aged
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage)
• Cyclodextrins (administration & dosage)
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Drug Therapy, Combination
• Female
• Follow-Up Studies
• Humans
• India
• Male
• Middle Aged
• Osteoarthritis (diagnosis, drug therapy)
• Product Surveillance, Postmarketing
• Severity of Illness Index
• Sulfonamides (administration & dosage)
• Treatment Outcome
• beta-Cyclodextrins