Abstract | BACKGROUND: Conifer seeds are used for food preparation in several countries. Aim of the study To assess the lipid-lowering and antiatherogenic properties of maritime pine (Pinuspinaster) seed oil. METHODS: The effects of maritime pine oil supplementation (20% w/w) for 2 weeks were compared to those of coconut and sunflower oil in mice expressing human apolipoprotein B (hApoB). Atherosclerosis lesion development was measured in hApoB mice fed 1.25% (w/w) cholesterol and 0.05% (w/w) sodium cholate and either coconut, sunflower or maritime pine oil (20% w/w) for 8 weeks. RESULTS: CONCLUSIONS: Feeding maritime pine oil is associated with major changes of lipid and lipoprotein levels in hApoB mice. However, in the long term, maritime pine oil has no preventive effect on cholesterol-induced aortic lesion development in hApoB mice.
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Authors | G Asset, E Baugé, R L Wolff, J C Fruchart, J Dallongeville |
Journal | European journal of nutrition
(Eur J Nutr)
Vol. 40
Issue 6
Pg. 268-74
(Dec 2001)
ISSN: 1436-6207 [Print] Germany |
PMID | 11876490
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Apolipoproteins B
- Cholesterol, Dietary
- Cholesterol, LDL
- Dietary Fats, Unsaturated
- Lipoproteins
- Phospholipids
- Plant Oils
- Sunflower Oil
- Triglycerides
- Cholesterol
- Coconut Oil
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Topics |
- Animals
- Apolipoproteins B
(genetics)
- Arteriosclerosis
(chemically induced, pathology, prevention & control)
- Cholesterol
(blood)
- Cholesterol, Dietary
(administration & dosage)
- Cholesterol, LDL
(blood)
- Chromatography, Gel
- Coconut Oil
- Dietary Fats, Unsaturated
(pharmacology)
- Female
- Gene Expression
- Humans
- Lipoproteins
(blood)
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Phospholipids
(blood)
- Pinus
- Plant Oils
(pharmacology)
- Seeds
- Sunflower Oil
- Triglycerides
(blood)
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