Topical chloramphenicol for eye infections.

Abstract

Topical chloramphenicol has been widely used in the treatment and prevention of superficial eye infections due to its broad spectrum of activity and low cost. The use of this drug has decreased considerably in the United States since the first case of aplastic anaemia associated with topical chloramphenicol was reported in the 1960s. This medication, however, is still widely used in many other countries. This paper evaluates the evidence for and against the use of topical chloramphenicol in ocular diseases.

• Authors: R F Lam, J S M Lai, J S K Ng, S K Rao, R W K Law, D S C Lam
• Journal: Hong Kong medical journal = Xianggang yi xue za zhi (Hong Kong Med J) Vol. 8 Issue 1 Pg. 44-7 (Feb 2002) ISSN: 1024-2708 [Print] China
• PMID: 11861993 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Anti-Bacterial Agents
• Ophthalmic Solutions
• Chloramphenicol

Topics

• Administration, Topical
• Anemia, Aplastic (chemically induced)
• Anti-Bacterial Agents (administration & dosage, adverse effects)
• Chloramphenicol (administration & dosage, adverse effects)
• Eye Infections, Bacterial (drug therapy)
• Humans
• Ophthalmic Solutions