A double-blind controlled trial of 'Gaviscon' in patients with symptomatic gastro-oesophageal reflux.

Abstract

In a double-blind trial in 26 patients with symptomatic gastro-oesophageal reflux, the alginate/effervescent/antacid compound 'Gaviscon' was compared with antacid containing placebo similarly formulated. Retrosternal pain after meals and at night was significantly reduced whilst patients were taking 'Gaviscon' and the beneficial effects lasted for many weeks after discontinuation of the active preparation.

• Authors: D E Barnardo, M Lancaster-Smith, I D Strickland, J T Wright
• Journal: Current medical research and opinion (Curr Med Res Opin) Vol. 3 Issue 6 Pg. 388-91 ( 1975) ISSN: 0300-7995 [Print] England
• PMID: 1183220 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Alginates
• Antacids
• Bicarbonates
• Silicic Acid
• Aluminum Hydroxide
• Magnesium

Topics

• Alginates (therapeutic use)
• Aluminum Hydroxide (therapeutic use)
• Antacids (therapeutic use)
• Bicarbonates (therapeutic use)
• Gastroesophageal Reflux (prevention & control)
• Humans
• Magnesium (therapeutic use)
• Silicic Acid (therapeutic use)