Abstract |
The purpose of this study was to compare Bio-Oss (BO), an anorganic bovine bone xenograft, in combination with Bio-Gide (BG), a bioabsorbable collagen barrier, to open-flap debridement (OFD) surgery in human mandibular Class II furcation defects. A total of 31 furcations (18 treatment, 13 control) in 21 patients were treated. There was a statistically significant improvement in most clinical indices for the BO/BG group, with minimal improvement noted for the OFD group. Vertical probing depth reduction of 2.0 mm and horizontal probing depth reduction of 2.2 mm were noted for the BO/BG group, with 0.3 mm and 0.2 mm reductions, respectively, noted for OFD. Hard tissue measurements showed 2.0 mm of vertical furcation bone fill for BO/BG and 0.5 mm for OFD. The BO/BG group had 3.0 mm of horizontal furcation bone fill, and the OFD group had 0.9 mm. The BO/BG group had a defect resolution of 82.7%; 42.5% was noted for the OFD group. There was a statistically significant difference between BO/BG and OFD in all soft and hard tissue measurements with the exception of attachment level, recession, and alveolar crest resorption.
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Authors | B E Houser, J T Mellonig, M A Brunsvold, D L Cochran, R M Meffert, M E Alder |
Journal | The International journal of periodontics & restorative dentistry
(Int J Periodontics Restorative Dent)
Vol. 21
Issue 2
Pg. 161-9
(Apr 2001)
ISSN: 0198-7569 [Print] United States |
PMID | 11829390
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Bio-Gide
- Bio-Oss
- Bone Substitutes
- Membranes, Artificial
- Minerals
- Collagen
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Topics |
- Absorbable Implants
- Alveolar Process
(pathology)
- Analysis of Variance
- Animals
- Bone Matrix
(transplantation)
- Bone Regeneration
(physiology)
- Bone Substitutes
(therapeutic use)
- Cattle
- Collagen
(therapeutic use)
- Debridement
- Female
- Follow-Up Studies
- Furcation Defects
(classification, pathology, surgery)
- Gingival Recession
(pathology, surgery)
- Humans
- Male
- Mandible
(pathology, surgery)
- Membranes, Artificial
- Middle Aged
- Minerals
(therapeutic use)
- Molar
(pathology, surgery)
- Periodontal Attachment Loss
(pathology, surgery)
- Single-Blind Method
- Statistics as Topic
- Surgical Flaps
- Transplantation, Heterologous
- Treatment Outcome
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