Abstract | BACKGROUND: A 64-year-old man was admitted to our hospital with significant weight loss and symptoms of fatigue. He had normocytic anaemia and absolute neutropenia in peripheral blood. MATERIAL AND METHODS: Further haematological and endocrinological investigations were performed. RESULTS: Bone marrow aspiration and biopsy showed dysplastic signs. Immunophenotyping and cytogenetics did not provide evidence of primary haematological disease. Endocrinological testing demonstrated secondary adrenal insufficiency. Magnetic resonance imaging of the sella turcica showed an empty sella. Cortisol substitution eliminated the symptoms of the patient and normalised his peripheral blood values. The disturbed maturity and hypoplasia of the bone marrow were also normalised. INTERPRETATION:
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Authors | R F Hallstensen, J Svartberg, V Isaksen, R Bajic, M L Løchen, J B Hansen |
Journal | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
(Tidsskr Nor Laegeforen)
Vol. 121
Issue 29
Pg. 3391-4
(Nov 30 2001)
ISSN: 0029-2001 [Print] Norway |
Vernacular Title | Anemi og nøytropeni ved primaert tom sella-syndrom. |
PMID | 11826783
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Adult
- Anemia
(complications, diagnosis)
- Bone Marrow
(pathology)
- Bone Marrow Examination
- Diagnosis, Differential
- Empty Sella Syndrome
(blood, complications, diagnosis, physiopathology)
- Hematopoiesis
(physiology)
- Hemoglobins
(analysis)
- Humans
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Neutropenia
(complications, diagnosis)
- Sella Turcica
(pathology)
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