[Current medical possibilities in the treatment of arthrosis].

Abstract

DRUG CLASSES: Three drug classes can be distinguished. The first includes drugs used for symptomatic care. This class includes a subclass of rapid action drugs (antalgesics, nonsteroidal antiinflammatory drugs, NSAID) and a subclass of symptomatic slow acting drugs. The second class corresponds to antiosteoartritis drugs called chondroprotective drugs or structure modifying. The third class includes drugs used for local care.

TREATMENT STRATEGY:

For episodes of acute pain, the first intention prescription should include rapid action drugs for symptomatic relief (paracetamol then NSAID). A symptomatic slow acting antiosteoarthritis drug can also be associated then continued after interrupting the rapid action symptomatic drugs. Diacerein is a drug with prolonged antiosteoarthritis action that has proven efficacy for symptom relief equi-valent to NSAID assessed in terms of pain relief and function: the ECHODIAH study provides arguments favoring its chondromodulating effect.

• Authors: B Avouac
• Journal: Presse medicale (Paris, France : 1983) (Presse Med) Vol. 31 Issue 1 Pt 2 Pg. 5-6 (Jan 12 2002) ISSN: 0755-4982 [Print] France
• Vernacular Title: Possibilités thérapeutiques médicales actuelles de l'arthrose.
• PMID: 11826590 (Publication Type: English Abstract, Journal Article)

Topics

• Humans
• Osteoarthritis (drug therapy)