| Abstract | OBJECTIVES: To investigate the effectiveness of splenectomy in patients with idiopathic thrombocytopenic purpura who failed to respond to conservative management. METHOD: Sixty-three patients were treated with splenectomy and followed up for 2 months to 16 years (average 4.7 years). RESULT: The patients had symptoms of bleeding and their platelet count on average was 24 x 10(9)/L. The first, 3rd, 5th and 7th day after operation, the average platelet count was 110 x 10(9)/L, 202 x 10(9)/L, 251 x 10(9)/L and 246 x 10(9)/L. Their platelet recovered to normal during a week in 51 cases (80.9%). The total effective rate was 86.9% after follow-up for 2 months. The recurrence rate was 17.9% in 39 cases after follow-up for longtime. CONCLUSIONS: The curative effect of splenectomy is better in children than in adults. In patients with increased platelet have a favourable prognosis. Splenectomy is safe and effective in the treatment of idiopathic thrombocytopenic purpura. |
| Authors | J Zhu, X Leng, N Dong, F Wang, L Huang, X Zhu, R Du
(Affiliation: Department of Surgery, People's Hospital, Beijing Medical University, Beijing 100044.)
|
| Journal | Zhonghua wai ke za zhi [Chinese journal of surgery]
(Zhonghua Wai Ke Za Zhi)
Vol. 36
Issue 5
Pg. 287-9
(May 1998)
ISSN: 0529-5815 China |
| PMID | 11825389
(Publication Type: English Abstract, Journal Article)
|
| Topics |
- Adolescent
- Adult
- Child
- Chronic Disease
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Purpura, Thrombocytopenic, Idiopathic
(surgery)
- Splenectomy
- Treatment Outcome
|
