The use of tiagabine in affective disorders.

Abstract

We reviewed the available literature on the efficacy of a novel anticonvulsant, Tiagabine (TGB), in the treatment of bipolar disorder. Study results indicate that TGB does not represent a valid option in acute mania due its required slow, progressive titration. More rapid titration schemes may lead to severe complications. TGB may be an option as an adjunct long-term treatment approach in refractory patients, but further studies are clearly needed to support this.

• Authors: M G Carta, M C Hardoy, H Grunze, B Carpiniello
• Journal: Pharmacopsychiatry (Pharmacopsychiatry) Vol. 35 Issue 1 Pg. 33-4 (Jan 2002) ISSN: 0176-3679 [Print] Germany
• PMID: 11819159 (Publication Type: Journal Article, Review)

Chemical References

• Anticonvulsants
• Nipecotic Acids
• Tiagabine

Topics

• Anticonvulsants (therapeutic use)
• Bipolar Disorder (drug therapy)
• Humans
• Mood Disorders (drug therapy)
• Nipecotic Acids (therapeutic use)
• Tiagabine