[Outcome of antibiotic therapy in patients with hemorrhagic fever with renal syndrome].

Abstract

AIM:

To evaluate effects of antibiotics in the treatment of hemorrhagic fever with renal syndrome (HFRS).

MATERIAL AND METHODS:

Clinico-laboratory comparisons were conducted in patients with HFRS who received antibiotics (n = 153) and did not (n = 104) in combined treatment of their disease.

RESULTS:

HFRS patients treated with antibiotics had weakness, poor appetite, hyperemia of the face, enanthema, hemorrhagic eruption, coated tongue, abdominal distention, thirst, xerostomia, oligoanuria, polyuria significantly longer. Antibiotics raise blood levels of urea and creatinine, urinary levels of protein, ESR, later normalization of renal function, number of plasmic cells and eosinophils, etc.

CONCLUSION:

This study evidently shows a negative influence of antibiotics on the course of hemorrhagic fever with renal syndrome.

• Authors: Iu N Sidel'nikov, A Iu Martynenko
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 73 Issue 11 Pg. 78-81 ( 2001) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Posledstviia antibiotikoterapii u bol'nykh s gemorragicheskoĭ likhoradkoĭ s pochechnym sindromom.
• PMID: 11806215 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Adult
• Anti-Bacterial Agents (adverse effects)
• Female
• Hemorrhagic Fever with Renal Syndrome (drug therapy, physiopathology, urine)
• Humans
• Kidney (physiopathology)
• Male