Bronchoalveolar lavage for the diagnosis and treatment of pneumonia associated with transport in Thoroughbred racehorses.

Abstract

To evaluate a hypothese that use of bronchoalveolar lavage (BAL) for early treatment of pneumonia would improve their prognosis by reducing bacterial numbers and excessive numbers of neutrophils in the lung, initial experiences with BAL in the diagnosis and treatment of pneumonia were performed in 36 racehorses that became ill within 24 hr of long distance travel (1,200-1,600 km, 26-32 hr) by road. Comparisons were made of the outcomes of the 36 horses and those of 42 horses (81.0% recovered, 50.0% returned to racing) treated for transport associated pneumonia without BAL. The total amount of BAL fluid injected during hospitalization varied from 700 to 3,700 ml and the duration of antibiotic treatments ranged from 5 to 40 days. Clinical symptoms after lavages showed good results with no side effects. None of the horses required thoracic drainage. Horses treated with BAL required shorter period of antibiotic therapy, a greater percentage recovered (100%, 36/36) and a greater percentage returned to racing (77.8%, 28/36). Eight (22.2%) never raced because of lameness or other considerations.

• Authors: S Ito, S Hobo, D Eto, H Sato
• Journal: The Journal of veterinary medical science (J Vet Med Sci) Vol. 63 Issue 12 Pg. 1263-9 (Dec 2001) ISSN: 0916-7250 [Print] Japan
• PMID: 11789602 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Animals
• Anti-Bacterial Agents (therapeutic use)
• Bronchoalveolar Lavage (veterinary)
• Bronchoalveolar Lavage Fluid (chemistry, microbiology)
• Female
• Horse Diseases (drug therapy, microbiology, therapy)
• Horses
• Japan
• Leukocyte Count (veterinary)
• Male
• Pasteurellosis, Pneumonic (drug therapy, microbiology, therapy)
• Statistics, Nonparametric
• Treatment Outcome