[Apropos of 2 rare severe surgical complications from the use of intramuscular and intrarectal quinine].

Abstract

Quinine by intramuscular or intrarectal injection has been found to be the best treatment for malaria in Niger, particularly in field health centres where the use of solutions can pose problems. There have been several reports of complications following injections, usually due to technical error or to the toxic side effects of quinine. In our hospital, we treated two such rare complications consisting of a case of coxal osteoarthritis induced by intramuscular injection and a case of anorectal necrotising induced by intrarectal injection. The occurrence of such life-threatening events could be reduced in frequency by teaching health personnel about techniques of quinine administration as well as its dangers.

• Authors: Y Harouna, Y Gamatie, S Gamatie, H Mounkaila, M Boureima
• Journal: Bulletin de la Societe de pathologie exotique (1990) (Bull Soc Pathol Exot) Vol. 93 Issue 5 Pg. 328-30 (Jan 2000) ISSN: 0037-9085 [Print] France
• Vernacular Title: A propos de deux complications chirurgicales rares graves de l'usage de la quinine intra-musculaire et intra-rectale.
• PMID: 11775318 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Quinine

Topics

• Administration, Rectal
• Adolescent
• Anus Diseases (chemically induced)
• Humans
• Infant
• Injections
• Injections, Intramuscular
• Malaria (drug therapy)
• Male
• Necrosis
• Niger
• Osteoarthritis, Hip (chemically induced)
• Quinine (administration & dosage, adverse effects)
• Rectum (drug effects)