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Population-based survey of antimicrobial susceptibility and serotype distribution of Streptococcus pneumoniae from meningitis patients in Salvador, Brazil.

Abstract
Penicillin-nonsusceptible strains were isolated from 15% of 303 individuals with pneumococcal meningitis identified during a 4-year surveillance study in Salvador, Brazil. The estimated rate of coverage of the seven-valent conjugate vaccine was 74% among patients <5 years of age and 94% among those infected with nonsusceptible isolates, indicating that the use of conjugate vaccines may be an approach to the control of emerging penicillin resistance in Brazil.
AuthorsJoice Neves Reis, Soraia Machado Cordeiro, Steven J Coppola, Kátia Salgado, Maria G S Carvalho, Lúcia M Teixeira, Terry A Thompson, Richard R Facklam, Mitermayer G Reis, Albert I Ko
JournalJournal of clinical microbiology (J Clin Microbiol) Vol. 40 Issue 1 Pg. 275-7 (Jan 2002) ISSN: 0095-1137 [Print] United States
PMID11773131 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Anti-Bacterial Agents
Topics
  • Anti-Bacterial Agents (pharmacology)
  • Brazil (epidemiology)
  • Child
  • Child, Preschool
  • Humans
  • Meningitis, Pneumococcal (epidemiology, microbiology)
  • Microbial Sensitivity Tests
  • Penicillin Resistance
  • Population Surveillance
  • Serotyping
  • Streptococcus pneumoniae (classification, drug effects)

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